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“Our aim is to understand woman reproductive growing older, and why fertility swiftly declines setting up during the mid-30s,” states Satoshi Namekawa, a professor of Microbiology and Molecular Genetics, in whose lab Munakata works.
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Do the job by Namekawa and Munakata indicates that a crucial occasion happens around the time of birth: the nascent egg cells enter a holding pattern, with their DNA precisely packaged and primed for fertilization later in life.
The grant from the Global Consortium for Reproductive Longevity and Equity (GCRLE) was declared in June. It is going to offer $two hundred,000 in funding, spread around two yrs. With it, Munakata will examine slightly-recognized facet of reproductive biology: the way in which an egg mobile stops expanding and enters a holding sample, correct within the time a feminine is born.
“We don’t understand how these cells are maintained for decades,” suggests Namekawa. “We want to know The key of this system.
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This protein may perhaps “set up and manage the chromatin condition,” says Namekawa — trying to keep the spools in place plus the oocytes genetically primed because the mouse matures.
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